10-1367
Spautin-1
Size
£163.00
- SKU:
- 10-1367
- Physical State:
- Solid
- Molecular Weight:
- 271.27
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1262888-28-7
- Immunogen:
- Protease
- Extra Details:
- A specific and potent autophagy inhibitor. Spautin-1 promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin-specific proteases USP10 and USP13 which target the Beclin-1 subunit of Vps34 complexes1. Deranges dengue virion maturation2. Inhibits autophagy in a Beclin-1 independent manner in primary epithelial ovarian cancer cells3. Selectively induces cell death of mutant p53-expressing cancer cell lines under confluency4. Cell permeable.
- Shipping Conditions:
- Ambient