10-1337
Garcinol
Size
£168.00
- SKU:
- 10-1337
- Physical State:
- Solid
- Molecular Weight:
- 602.80
- Purity:
- >95%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 78824-30-3
- ABP:
- No Import Docs
- Immunogen:
- Acetyltransferase
- Extra Details:
- Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7uM and PCAF IC50=5uM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2
- Shipping Conditions:
- Ambient