10-1327
A83-01
Size
£149.00
- SKU:
- 10-1327
- Physical State:
- Solid
- Molecular Weight:
- 421.53
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 909910-43-6
- ABP:
- No Import Docs
- Immunogen:
- Kinase
- Extra Details:
- Potent and selective ALK4, 5 and 7 inhibitor1,2. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFB Beta2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency3. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts4. Cell permeable. Active in vivo.
- Shipping Conditions:
- Ambient