Glyburide

Size

£129.00

SKU:: 10-1325
Additional Names:: Glibenclamide
Physical State:: Solid
Molecular Weight:: 494.01
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 10238-21-8
Immunogen:: Inflammasome|Ion channel
Extra Details:: Second generation oral hypoglycemic agent. Acts via ATP-dependent K+ channel (Kir6, KATP) block1. Inhibits Kir6 currents in the pancreas, causing an increase in intracellular Ca2+ and insulin secretion. Also inhibits recombinant CFTR Cl- channels with an IC50 of 20 uM2. Cell permeable.