Skip to content

Download Spec Sheet

download
  1. Shop all
  2. Antagonists

10-1309

MG-132

Size

£149.00

SKU:
10-1309
Additional Names:
Z-Leu-Leu-Leu-CHO
Physical State:
Solid
Molecular Weight:
475.63
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
133407-82-6
Immunogen:
Proteasome
Extra Details:
Specific inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50=100 nM with Z-LLL-AMC as substrate).1 Also inhibits calpain (IC50=1.25 uM)1 Suppresses gastric cancer cell proliferation and induces macro-autophagy2. Activates stress kinases and induces Hsp72.3 Induces neurite outgrowth.1 Blocks NFK KappaB activation by blocking IK KappaB proteolysis (IC50=3 uM).4 Cell permeable.
Shipping Conditions:
Ambient