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10-1283

Trifluorothymidine

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£144.00

SKU:
10-1283
Additional Names:
TFT|Trifluorothymine deoxyriboside|Trifluridine|A Alpha,A Alpha,A Alpha-Trifluorothymidine
Physical State:
Solid
Molecular Weight:
296.20
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
70-00-8
Immunogen:
DNA
Extra Details:
An analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes.3 Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.4
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Ambient