10-1268
Cytarabine
Size
£139.00
- SKU:
- 10-1268
- Additional Names:
- Ara-C|Arabinocytidine|Cytosine B Beta-D-Arabinofuranoside|U-19920A
- Physical State:
- Solid
- Molecular Weight:
- 243.22
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 147-94-4
- Immunogen:
- DNA|RNA
- Extra Details:
- A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML).6,7
- Shipping Conditions:
- Ambient