10-1266
Stavudine
Size
£151.00
- SKU:
- 10-1266
- Additional Names:
- BMY 27857|d4T
- Physical State:
- Solid
- Molecular Weight:
- 224.22
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 3056-17-5
- Immunogen:
- DNA|Inflammasome
- Extra Details:
- Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs).1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates AB Beta-induced autophagy in macrophages.4
- Shipping Conditions:
- Ambient