10-1244
Ingenol-3-angelate
Size
£206.00
- SKU:
- 10-1244
- Additional Names:
- PEP-005
- Physical State:
- Solid
- Molecular Weight:
- 460.53
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 75567-37-2
- Immunogen:
- Kinase
- Extra Details:
- Selective activator of protein kinase C which displays antileukemic activity mediated via PKC1 In contrast, it provides a strong survival signal to resting and activated human T cells via activation of PKC and downstream activation of NFB.2 Treatment of subcutaneous tumors results in anti-cancer CD8 T cells, also displays adjuvant activity and synergizes with cancer immunotherapies.3 Induces senescence-like growth arrest in solid tumor cells.4 Inhibits HIV-1 infection at an early pathway of viral entry.5
- Shipping Conditions:
- Ambient