Calyculin A

Size

POA

SKU:: 10-1230
Physical State:: White solid or film (Note. Vials may appear empty)
Molecular Weight:: 1009.18
Purity:: >98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 101932-71-2
Immunogen:: Phosphatase
Extra Details:: Calyculin A (101932-71-2) is a potent cell permeable inhibitor of protein phosphatase 1 (PP1) and 2A (PP2A), IC50=0.3-1 nM.1 Has no effect on PP2B, PP2C as well as acid or alkaline phosphatase at 1 mM.2 A non-phorbol tumor promoter.3 Stimulates the phosphorylation of various cellular proteins such as vimentin4 and NFkB5 and also induces membrane translocation of protein kinase C6.