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10-1212

2-APB

Size

£124.00

SKU:
10-1212
Physical State:
Solid
Molecular Weight:
225.1
Purity:
98%
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
524-95-8
Immunogen:
Ion channel
Extra Details:
An IP3 receptor antagonist (IC50=42 uM).1 Inhibits store-operated Ca2+ channels at high concentrations (50 uM) but stimulates at low concs. (<10 uM).2 Modulates TRP channels, blocking TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8, TRPP2 and at higher concentrations, activating TRPV1, TRPV2, TRPV3.3,4 Also inhibits selected GAP junction subtypes.5
Shipping Conditions:
Ambient