10-1211
ODQ
Size
£129.00
- SKU:
- 10-1211
- Physical State:
- Solid
- Molecular Weight:
- 187.15
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 41443-28-1
- Immunogen:
- Guanylyl cyclase
- Extra Details:
- A potent and selective inhibitor of soluble guanylyl cyclase (sGC), IC50 = 20 nM).1 ODQ acts via competition with NO for the heme site of sGC where it binds irreversibly.2 ODQ does not inhibit NO-mediated macrophage toxicity, an activity that is unrelated to cGMP nor does it inhibit particulate GC.1 ODQ is an extremely useful tool to explore the involvement of the NO-cGMP pathway in cellular signaling and physiologic processes.3-5
- Shipping Conditions:
- Ambient