10-1198
GSK-1016790A
Size
£166.00
- SKU:
- 10-1198
- Physical State:
- Solid
- Molecular Weight:
- 655.62
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 942206-85-1
- Immunogen:
- Ion channel
- Extra Details:
- A novel and potent TRPV4 channel agonist. GSK1016790A induced Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300-fold more potent than 4A Alpha-PDD and is a valuable tool for investigating the role of TRPV4 in physiological processes.
- Shipping Conditions:
- Ambient