10-1197
IU1
Size
£149.00
- SKU:
- 10-1197
- Physical State:
- Solid
- Molecular Weight:
- 300.38
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 314245-33-5
- Immunogen:
- DUB (Deubiquitinating enzyme)|Prions
- Extra Details:
- Selective inhibitor of Usp14 (IC50<4 uM). Enhances proteasome activity and substrate proteolysis.1,2 Inhibits Dengue virus replication.3 In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load.4 Attenuates ischemia/reperfusion-induced neuronal injury in a mouse model.5 Cell permeable.
- Shipping Conditions:
- Ambient