10-1150
P7C3
Size
£158.00
- SKU:
- 10-1150
- Physical State:
- Solid
- Molecular Weight:
- 474.20
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 301353-96-8
- Immunogen:
- Energy production
- Extra Details:
- P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity.1 Delays disease progression in G93A-SOD2 mutant mouse model of amyotrophic lateral sclerosis.2 Blocks MPTP-mediated cell death of dopaminergic neurons in the substantia nigra of adult mice, a model of Parkinson disease.3 Restores hippocampal neurogenesis in a mouse model of Down Syndrome.4 The mechanism of action involves activation of nicotinamide phosphoribosyltransferase (NAMPT) with concomitant increase of intracellular levels of NAD.5 Active in vivo.
- Shipping Conditions:
- Ambient