10-1144
Antazoline HCl
Size
£143.00
- SKU:
- 10-1144
- Physical State:
- Solid
- Molecular Weight:
- 301.82
- Purity:
- >98%
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2508-72-7
- Immunogen:
- GPCR|Ion channel
- Extra Details:
- Antazoline (2508-72-7) displays neuroprotective effects against hypoxia-induced death in neuronal cultures, the mechanism of action being inhibition of NMDA currents (IC50=4 uM).1 It induces concentration-dependent stimulation of insulin secretion in rat pancreas which is mediated via imidazoline I1 receptors.2 It also acts as a histamine H1 receptor antagonist (Ki=38.4 nM, human recombinant H1 receptor)3 and was found to be a highly effective antiarrhythmic agent4.
- Shipping Conditions:
- Ambient