Retinoic acid

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£129.00

SKU:: 10-1138
Additional Names:: ATRA|Tretinoin
Physical State:: Solid
Molecular Weight:: 300.44
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 302-79-4
Immunogen:: Retinoid receptor and related|Transcription factor
Extra Details:: All-trans-Retinoic acid (ATRA; a metabolite of Vitamin A) is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 ATRA promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4