10-1127
AP-18
Size
£163.00
- SKU:
- 10-1127
- Physical State:
- Solid
- Molecular Weight:
- 209.67
- Purity:
- 98%
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- CAS Number:
- 55224-94-7
- Immunogen:
- Ion channel
- Extra Details:
- TRPA1 channel blocker IC50=3.1-4.5 uM in various cell lines. Reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. Does not block TRPV1, V2, V3, V4 or M8 at concentrations up to 50 uM.1 Blocks TRPA1 pore dilation (IC50=10.3 uM).2 An important tool for assessing the role of TRPA1 in cell signaling and physiological processes.3-5
- Shipping Conditions:
- Ambient