Sulindac Sulfone

Size

£149.00

SKU:: 10-1122
Physical State:: Solid
Molecular Weight:: 372.41
Purity:: >98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 59864-04-9
Immunogen:: PDE (Phosphodiesterase)
Extra Details:: Metabolite of the cyclooxygenase inhibitor sulindac that induces apoptosis via inhibition of type 5 phosphodiesterases.1 Sulindac sulfone does not inhibit cyclooxygenase at physiological concentrations but does inhibit K-ras-dependent cyclooxygenase-2 expression in colon cancer cells.2