Thalidomide

Size

£149.00

SKU:: 10-1115
Physical State:: Solid
Molecular Weight:: 258.25
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 50-35-1
Immunogen:: Molecular glue|Ubiquitin ligase
Extra Details:: Binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution, compound is teratogenic.