10-1104
Rapamycin
Size
£151.00
- SKU:
- 10-1104
- Additional Names:
- AY-22989|NSC-226080|Rapamune|Sirolimus|WY-090217
- Physical State:
- Solid
- Molecular Weight:
- 914.17
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 53123-88-9
- Immunogen:
- Antibiotic|Kinase|PPIase
- Extra Details:
- Clinically useful immunosuppressant. Inhibits the response to interleukin-2 blocking activation of T- and B-cells.1 Rapamycin forms a complex with cytosolic FK-binding protein 12 (FKB12) that binds to mTOR Complex1(mTORC1) inhibiting the mammalian target of rapamycin (mTOR).2 Also binds to mTORC2 leading to decreased glucose tolerance and insensitivity to insulin.3 Induces autophagy.4
- Shipping Conditions:
- Ambient