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£152.00

SKU:: 10-1102
Additional Names:: ONO-5046
Physical State:: Solid
Molecular Weight:: 456.45
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 127373-66-4
Immunogen:: Protease
Extra Details:: Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other proteases. Inhibits NF-K KappaB activation2 and LTB4-induced neutrophil migration in vitro3. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo4.