A-803467

Size

£149.00

SKU:: 10-1066
Physical State:: Solid
Molecular Weight:: 357.80
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 944261-79-4
Immunogen:: Ion channel
Extra Details:: Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Nav1.8 are 140 nM and 8.0 nM respectively.