STO-609

Size

£173.00

SKU:: 10-1036
Physical State:: Solid
Molecular Weight:: 314.30 ∙ 60.05
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 52029-86-4
Immunogen:: Kinase
Extra Details:: Selective inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki = 80 and 15 ng/ml for inhibition of CaM-KKA Alpha and CaM-KKB Beta respectively).1 Binds to the ATP-binding site.2 Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. Important tool for probing distinct CaMK pathways in LTP.3 Reduces starvation-induced autophagosomal membrane formation.4 Reverses age-associated decline in bone mass.5 Stimulates osteoblast formation, inhibits osteoclast differentiation.6