SP-600125

Size

£153.00

SKU:: 10-1033
Additional Names:: 1,9-Pyrazoloanthrone
Physical State:: Solid
Molecular Weight:: 220.23
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 129-56-6
Immunogen:: Kinase
Extra Details:: Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50's range from 40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.