10-1030
ZM-336372
Size
£158.00
- SKU:
- 10-1030
- Physical State:
- Solid
- Molecular Weight:
- 389.46
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 208260-29-1
- Immunogen:
- Kinase
- Extra Details:
- Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50uM) with the exception of p38 (SAPK2A Alpha) (IC50=2uM) and SAPK2B Beta (p38B Beta) (IC50=2uM). Induces a paradoxical >100-fold activation of c-Raf in whole cells. Induces apoptosis in a variety of cell lines. Cell permeable.
- Shipping Conditions:
- Ambient