Dorsomorphin

Size

£158.00

SKU:: 10-1029
Additional Names:: Compound C
Physical State:: Solid
Molecular Weight:: 399.49
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 866405-64-3
Immunogen:: Kinase
Extra Details:: Potent, selective and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM).1 It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. It inhibits bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6).2 Dorsomorphin has been shown to promote cardiomyogenesis in mouse embryonic stem cells (ESCs) in vitro.3 Induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.4