Pioglitazone HCl

Size

£139.00

SKU:: 10-1010
Physical State:: Solid
Molecular Weight:: 392.090
Purity:: 98%
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 112529-15-4
Immunogen:: Transcription factor
Extra Details:: Pioglitazone is a clinically useful antidiabetic drug.1 It is a selective agonist of the human peroxisome proliferator-activated receptor 1(PPAR; EC50 = 490 nM2, 550nM3) with weak agonist activity at PPAR and no activity at PPAR.2 Inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes.4 Suppresses production of inflammatory cytokines and shows antidepressant-like activity in mouse models.5