Rabbit anti Human anticoagulation Factor IX

Cannot supply to this region.

SKU:: NM-RAHU-FIX
Source:: Factor IX is a vitamin K-dependent glycoprotein, MW 55,400, and it consists of a single polypeptide chain. It is synthesized in the liver, stable for several days in fresh blood and for many months in fresh frozen plasma. It can be prepared as a stable concentrate. Its physicochemical properties are similar to those of several other clotting factors, which makes separation particularly difficult. Factor IX is converted to FIXa by FXIa in the presence of calcium ions. Platelets possess FXI-like activity, bypassing FXII an XI. FIXa has a molecular weight of 46,500 and is composed of two chains linked by disulphide bonds. For immunization purposes, FIX can be obtained n highly purified form from fresh plasma concentrates. After coagulation, FIX antigen is also present in serum. Abnormal molecular variants are defective in proteolytic activation and serine protease activity, while calcium binding is also impaired. Freund's complete adjuvant is used in the first step of the immunization procedure.
Supplier:: Exalpha / Nordic Mubio
Host:: Rabbit
Formulation:: Delipidated, heat inactivated, lyophilized, stable whole serum. No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled rabbit serum. No f
Clonality:: Polyclonal
Format:: Delipidated, heat inactivated, lyophilized, stable whole serum. No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled rabbit serum. No f

Shipping Conditions:: Ambient