ELAB6940-R
SOX2 Monoclonal Antibody
Size
£344.70
Was £383.00
- SKU:
- ELAB6940-R
- Additional Names:
- SOX2
- Application:
- IHC-P
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Protect from light.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Extra Details:
- The SOX2 gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors, which plays an important role in early organ development. SOX2 can be used in the auxiliary diagnosis of germ cell tumors. 90% of embryonic cancers express SOX2, but not in seminoma, yolk sac tumor and choriocarcinoma. SOX2 has been shown to be a negative prognostic factor and associated with aggressive phenotypes in breast, head and neck, gastric, colorectal and bladder cancers. In small cell lung cancers, SOX2 was also correlated with a poor prognosis. Conversely, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and was shown to be an independent positive prognostic marker.
- Shipping Conditions:
- Blue Ice