E-OSEL-S0002
QuicKey Pro Sheep Cortisol ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-OSEL-S0002
- Additional Names:
- Cortisol
- Application:
- ELISA
- Physical State:
- Plasma, Serum
- Species Reactivity:
- Sheep
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Competitive
- Extra Details:
- Cortisol is the primary endogenous adrenal steroid in most mammals, including humans, whereas corticosterone is the primary adrenal corticosteroid in laboratory rodents . Rats and mice do not produce appreciable cortisol, because they lack the adrenocortical zona fasciculata enzyme 17-A Alpha hydroxylase (CYP17) . The absence of 17,20 lyase activity of CYP17 also accounts for the lack of adrenal androgen production in laboratory rodents . However, most mammals, including humans, produce both cortisol and corticosterone, albeit the latter at lower circulating concentrations . More importantly, there is functional, evolutionary, and clinical significance to the difference in the structures of cortisol and corticosterone demonstrated by their differing affinities for the glucocorticoid and mineralocorticoid receptors . Furthermore, the inactive steroid cortisone is also found in significant concentrations in cortisol-producing species, including humans .
- Shipping Conditions:
- Blue Ice