E-OSEL-R0019
QuicKey Pro Rat PAI1 (Plasminogen Activator Inhibitor 1) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-OSEL-R0019
- Additional Names:
- SERPINE1,PAI,PAI1,PLANH1,Endothelial Plasminogen Activator Inhibitor
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Rat
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P20961
- Synonyms:
- endothelial plasminogen activator inhibitor;PAI;PAI-1;Pai1;PAI1A;Pai1aa;Planh;plasminogen activator inhibitor 1;RATPAI1A;serine (or cysteine) peptidase inhibitor, clade E, member 1;serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;serine (or cysteine) proteinase inhibitor, clade E, member 1;serine (or cysteine) proteinase inhibitor, member 1;serpin E1;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Extra Details:
- PAI-1 (plasminogen activator inhibitor-1) is a member of the serine protease inhibitor family. It is the main negative regulator of the fibrinolytic system, preventing plasminogen from converting into plasmin by inhibiting tissue-type plasminogen activator and urokinase-type plasminogen activator, thereby inhibiting fibrin degradation. It is mainly secreted by vascular endothelial cells, adipocytes, hepatocytes, platelets, and smooth muscle cells. The core function of PAI-1 is to regulate the balance between fibrinolysis and coagulation. However, its overexpression is associated with various diseases, including thrombotic disorders, fibrotic diseases, metabolic syndrome and obesity, and cancer.
- Shipping Conditions:
- Blue Ice