E-OSEL-M0023
QuicKey Pro Mouse IL-6R (Interleukin 6 Receptor) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-OSEL-M0023
- Additional Names:
- IL6R,CD126,IL-6R-1,IL-6R-Alpha,IL6Q,IL6RA,IL6RQ,gp80
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P22272
- Synonyms:
- CD126;I;IL;IL-6 receptor alpha chain;IL-6 receptor subunit alpha;IL-6R;IL-6R 1;IL-6R subunit alpha;IL-6R-alpha;IL-6RA;Il6r;interleukin-6 receptor subunit alpha
- Extra Details:
- Part of the receptor for interleukin 6. Binds to IL6 with low affinity,but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response,acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling',the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively,'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
- Shipping Conditions:
- Blue Ice