E-OSEL-M0005
QuicKey Pro Mouse IgG(Immunoglobulin G) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-OSEL-M0005
- Additional Names:
- Ighg
- Application:
- ELISA
- Physical State:
- Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P01863
- Synonyms:
- Immunoglobulin heavy chain gamma polypeptide
- Extra Details:
- There are five classes of mammalian immunoglobulins:IgA, IgD, IgE, IgM, and IgG. IgG is the most abundant immunoglobulinand is equally distributed in blood and tissue. In mice, the IgG class isfurther divided into four subclasses: IgG1, IgG2a IgG2c (strain specific),IgG2b, and IgG3. The general immunoglobulin structure is composed offour polypeptide chains, two heavy and two light chains linkedtogether and to each other by disulfide bonds, creating a tetramericquaternary structure. The resulting tetramer creates two identicalhalves which together form a Y like structure. While the amino-terminalportions that exhibits highly variable amino-acid composition areinvolved in antigen binding, the C terminal constant parts are involvedin complement binding, placental passage and binding to cellmembrane. IgG is involved in response to a foreign antigen. Thepresence of IgG usually signifies a mature antibody response. IgG has amolecular weight of about 150 kDa, it can bind to many pathogensand also plays an important role in antibody-dependent cell-mediatedcytotoxicity. Typically, mouse serum and plasma samples containabout 7 to 10 mgml of IgG.
- Shipping Conditions:
- Blue Ice