E-MSEL-R0005
Mini Sample Rat ACE2 (Angiotensin I Converting Enzyme 2) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-MSEL-R0005
- Additional Names:
- ACE-related carboxypeptidase
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Rat
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- Q5EGZ1
- Synonyms:
- ACE-related carboxypeptidase;angiotensin I converting enzyme (peptidyl-dipeptidase A) 2;angiotensin-converting enzyme 2;anigotensin-converting enzyme-related carboxypeptidase;renal angiotensin-converting enzyme 2
- Extra Details:
- Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II. Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin. Also cleaves other biological peptides, such as apelins, casomorphins and dynorphin A. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity
- Shipping Conditions:
- Blue Ice