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E-MSEL-M0126

Mini Sample Mouse DKK3 (Dickkopf Related Protein 3) ELISA Kit

Size

£120.60

Was £134.00

SKU:
E-MSEL-M0126
Additional Names:
Dickkopf-related protein 3,Dickkopf-3,Dkk-3,mDkk-3
Application:
ELISA
Physical State:
Other Biological Fluid, Plasma, Serum
Species Reactivity:
Mouse
Storage Conditions:
2-8[o]C
Supplier:
Elabscience
Reactivities:
Mouse
Format:
Colorimetric method,ELISA,Sandwich
Uniprot:
Q9QUN9
Synonyms:
AW061014;C87148;dickkopf homolog 3;dickkopf-3;dickkopf-related protein 3;dkk-3;mDkk-3
Extra Details:
Dkk3 protein antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Shipping Conditions:
Blue Ice