Mini Sample Mouse CEACAM1 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 1) ELISA Kit

Size

£128.70

Was £143.00

SKU:: E-MSEL-M0124
Additional Names:: Cell adhesion molecule CEACAM1,Biliary glycoprotein 1 ,BGP-1,Biliary glycoprotein D,Carcinoembryonic antigen-related cell adhesion molecule 1,MHVR1,Murine hepatitis virus receptor,MHV-R,CD66a,Bgp,Bgp1
Application:: ELISA
Physical State:: Other Biological Fluid, Plasma, Serum
Species Reactivity:: Mouse
Storage Conditions:: 2-8[o]C
Supplier:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: P31809
Synonyms:: bb-1;Bg;Bgp;BGP-1;Bgp1;biliary glycoprotein 1;biliary glycoprotein D;C-CA;C-CAM;carcinoembryonic antigen 1;carcinoembryonic antigen 7;carcinoembryonic antigen-related cell adhesion molecule 1;Cc1;CD66;CD66a;Cea;Cea-;Cea-1;Cea-7;CEA-related cell adhesion molecule 1;Cea1;Cea7;hepatitis virus (MHV-4) susceptibility;hepatitis virus receptor;Hv;Hv-;Hv-2;Hv2;mCEA;mCEA1;MHV;Mhv-;Mhv-1;MHV-R;MHVR;MHVR1;mmCGM1;mmCGM1a;mmCGM2;murine hepatitis virus receptor
Extra Details:: Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner.Plays a role as coinhibitory receptor in immune response, insulin action and also functions as an activator during angiogenesis.Its coinhibitory receptor function is phosphorylation- and PTPN6 -dependent, which in turn, suppress signal transduction of associated receptors by dephosphorylation of their downstream effectors.Plays a role in immune response, of T-cells, natural killer (NK) and neutrophils.Upon TCR/CD3 complex stimulation, inhibits TCR-mediated cytotoxicity by blocking granule exocytosis by mediating homophilic binding to adjacent cells, allowing interaction with and phosphorylation by LCK and interaction with the TCR/CD3 complex which recruits PTPN6 resulting in dephosphorylation of CD247 and ZAP70.Also inhibits T-cell proliferation and cytokine production through inhibition of JNK cascade and plays a crucial role in regulating autoimmunity and anti-tumor immunity by inhibiting T-cell through its interaction with HAVCR2.

Shipping Conditions:: Blue Ice