E-MSEL-M0123
Mini Sample Mouse CD48 (Cluster Of Differentiation 48) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-MSEL-M0123
- Additional Names:
- CD48,BLAST-1,BCM-1,SLAMF2
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P18181
- Synonyms:
- AI449234;AW610730;Bcm-1;BCM1;BCM1 surface antigen;BLAS;BLAST;BLAST-1;BLAST1;CD48 antigen;HM48-1;MEM-102;MRC OX-45 surface antigen;Sgp-;Sgp-60;signaling lymphocytic activation molecule 2;SLAM family member 2;SLAMF2
- Extra Details:
- Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation.Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation.Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
- Shipping Conditions:
- Blue Ice