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E-MSEL-M0117

Mini Sample Mouse TRACP-5b (Tartrate Resistant Acid Phosphatase 5) ELISA Kit

Size

£128.70

Was £143.00

SKU:
E-MSEL-M0117
Additional Names:
ACP5,HPAP,TRACP,TRACP5a,TRACP5b,TRACP-5b,TRAP,TrATPase,TTRRAP
Application:
ELISA
Physical State:
Other Biological Fluid, Plasma, Serum
Species Reactivity:
Mouse
Storage Conditions:
2-8[o]C
Supplier:
Elabscience
Format:
Colorimetric method,ELISA,Sandwich
Uniprot:
Q05117
Synonyms:
acid phosphatase type V;T;tartrate-resistant acid ATPase;tartrate-resistant acid phosphatase type 5;TR;TR-AP;TRACP;TRAP;trATPase;type 5 acid phosphatase
Extra Details:
Tartrate-resistant acid phosphatases (TRAPIACPS) are metallic enzymes belonging to the acid phosphatase group that catalyze the conversion of orthophosphate monomers into alcohols and orthophosphates.It is a ferriglycoprotein synthesized with a 35kd monomeric proenzyme.ACP5 is involved in bone resorption and is secreted by active osteoclasts.1 Dephosphorylation of osteopontin, a bone matrix protein, subsequently promotes osteoclast detachment and migration.In colorectal cancer, ovarian cancer, breast cancer, melanoma and other cancers,ACP5 expression is associated with tumor progression.In vitro experiments have shown that down-regulated expression of ACP5 can promote the proliferation and invasion of tumor cells in colorectal cancer cell lines.In senum, ACPS has been used as a marker for thyroid metastasis, and in addition, Acps removes the lysosomal protein as a recognition marker for mannose 6-phosphate.Tartrate-resistant acid phosphatases (TRAPIACPS) are metallic enzymes belonging to the acid phosphatase group that catalyze the conversion of orthophosphate monomers into alcohols and orthophosphates. It is a ferriglycoprotein synthesized with a 35kd monomeric proenzyme.
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