E-MSEL-M0112
Mini Sample Mouse GRN (Granulin) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-MSEL-M0112
- Additional Names:
- GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P28798
- Synonyms:
- acrogranin;acrogranulin;epit;epithelin;epithelin/granulin;glycoprotein 88;glycoprotein of 88 Kda;GP88;granulins;P;PC cell-derived growth factor;PCDGF;PEPI;Pgrn;pr;proepithelin;progranulin
- Extra Details:
- Secreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation.Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes.Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB.In addition, functions as a wound-related growth factor that acts directly on dermal fibroblasts and endothelial cells to promote division, migration and the formation of capillary-like tubule structures.Also promotes epithelial cell proliferation by blocking TNF-mediated neutrophil activation preventing release of oxidants and proteases .Moreover, modulates inflammation in neurons by preserving neurons survival, axonal outgrowth and neuronal integrity .
- Shipping Conditions:
- Blue Ice