Mini Sample Mouse PAI1 ( Plasminogen Activator Inhibitor 1 ) ELISA Kit

Size

£128.70

Was £143.00

SKU:: E-MSEL-M0098
Additional Names:: Serpin E1,PAI,PAI1,PLANH1
Application:: ELISA
Physical State:: Other Biological Fluid, Plasma, Serum
Species Reactivity:: Mouse
Storage Conditions:: 2-8[o]C
Supplier:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: P22777
Synonyms:: endothelial plasminogen activator inhibitor;nexin, plasminogen activator inhibitor type 1;P;PA;PAI;PAI-1;PAI1;Pl;Planh1;plasminogen activator inhibitor 1;Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI);plasminogen activator inhibitor, type I;serine (or cysteine) proteinase inhibitor, clade E, member 1;serpin E1
Extra Details:: Serpin E1 is a member of the serine proteinase inhibitors (serpin) superfamily, which is divided into two groups: inhibitory and non- inhibitory serpins. Serpin E1 is the most important physiological inhibitor of tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA), and therefore is a key regulator of fibrinolysis via inhibition of the activation of the broad-spectrum serine protease plasmin. Serpin E1 forms a covalent bond with both t-PA and u-PA (1:1 molar ratio). It is known that several receptors (uPAR, LRP-1A, megalin, VLDLR, and LRP-1B) bind and mediate endocytosis of plasminogen activator-Serpin E1 complexes.