Mini Sample Mouse gp130 ( Glucoprotein 130 ) ELISA Kit

Size

£128.70

Was £143.00

SKU:: E-MSEL-M0088
Additional Names:: CD130,CDW130,IL-6RB,IL6ST,IR6RB,Interleukin 6 signal transducer
Application:: ELISA
Physical State:: Other Biological Fluid, Plasma, Serum
Species Reactivity:: Mouse
Storage Conditions:: 2-8[o]C
Supplier:: Elabscience
Format:: Colorimetric method,ELISA,Sandwich
Uniprot:: Q00560
Synonyms:: 5133400A03Rik;AA389424;BB405851;CD130;D13Ertd699;D13Ertd699e;gp13;gp130;IL-6 receptor subunit beta;IL-6R subunit beta;IL-6R-beta;IL-6RB;interleukin-6 receptor subunit beta;Interleukin-6 signal transducer;membrane glycoprotein 130;oncostatin-M receptor subunit alpha
Extra Details:: The protein encoded by this gene is a signal transducer shared by many cytokines , including interleukin 6 ( IL6 ) , ciliary neurotrophic factor ( CNTF ) , leukemia inhibitory factor ( LIF ) , and oncostatin M ( OSM ) . This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6 , a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus , can bypass the interleukin 6 receptor ( IL6R ) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.