E-MSEL-H0029
Mini Sample Human TIMP-1 (Tissue Inhibitors of Metalloproteinase 1) ELISA Kit
Size
£128.70
Was £143.00
- SKU:
- E-MSEL-H0029
- Additional Names:
- TIMP1,CLGI,EPA,EPO,HCI
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Elabscience
- Format:
- Colorimetric method,ELISA,Sandwich
- Uniprot:
- P01033
- Synonyms:
- CLGI;collagenase inhibitor;EPA;epididymis secretory sperm binding protein;EPO;erythroid potentiating activity;Erythroid-potentiating activity;fibroblast collagenase inhibitor;HCI;metalloproteinase inhibitor 1;TIMP;TIMP-1;tissue inhibitor of metalloproteinases 1
- Extra Details:
- Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro, but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
- Shipping Conditions:
- Blue Ice