E-KAB-0707
Human FGF1 Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0707
- Additional Names:
- FGF-1,ECGF,ECGF-beta,A-FGF,FGFA,ECGFA,ECGFB,FGF-Alpha,HBGF1,HBGF-1,ECGFB,GLIO703,Heparin-binding growth factor 1
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- FGF1
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P05230
- Synonyms:
- Acidic fibroblast growth factor;AFGF;beta-endothelial cell growth factor;ECGF;ECGF-beta;ECGFA;ECGFB;Endothelial cell growth factor;endothelial cell growth factor, alpha;endothelial cell growth factor, beta;FGF-1;FGF-alpha;FGFA;fibroblast growth factor 1;fibroblast growth factor 1 (acidic);GLIO703;HBGF-1;HBGF1;heparin-binding growth factor 1
- Extra Details:
- FGF-1,one of the most studied members of the fibroblast growth factor family,is a powerful mitogen exhibiting strong action on many different cell types. FGF-1 activity can be mediated not only by autocrine/paracrine pathways but also by an intracrine pathway. FGF-1 lacks a secretion signal peptide and is exported through a non-classical pathway. Endogenous FGF-1 is found in the nucleus of most cell types. Nuclear localization is required for FGF-1 mitogenic activity. FGF-1 promotes tumor development by promoting cancer cell proliferation and survival. Increased FGF-1 expression in early stages of many different cancers has been reported. Under oxidative stress,astrocytes can also release FGF-1 which stimulates ApoE/HDL generation in an autocrine manner for protection of the brain against oxidative stress. Involvement of FGF-1 in inflammation,cardioprotection,wound healing,adipocyte remodeling,and restenosis is also reported.
- Shipping Conditions:
- Blue Ice