E-KAB-0702
Mouse ALPL Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0702
- Additional Names:
- ALPL,AP-TNAP,APTNAP,HOPS,TNAP,TNSALP,alkaline phosphatase,liver/bone/kidney,TNALP
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Mouse
- Buffer:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Immunogen:
- ALPL
- Formulation:
- Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
- Uniprot:
- P09242
- Synonyms:
- Ak;Akp;Akp-2;Akp2;Alkaline phosphatase 2;alkaline phosphatase 2, liver;Alkaline phosphatase liver/bone/kidney isozyme;alkaline phosphatase, tissue-nonspecific isozyme;ALP;APTNAP;T;TNAP;TNSALP
- Extra Details:
- Alkaline phosphatases function physiologically as homodimers. They catalyze the hydrolysis of phosphomonoesters and release inorganic phosphate. In humans,four isoenzymes have been described: a tissue-nonspecific (TNAP) and three tissue-specific placental (PLAP),intestinal (IAP),and germ cell (GCAP). TNAP is a cell membrane-bound ecto-enzyme that releases inorganic phosphate from phosphate-enriched substrates. Also,ALPL induces the hydrolysis of extracellular inorganic pyrophosphate (PPi) which is a potent endogenous inhibitor of calcification both in vivo and in vitro. Increased activity of the enzyme alkaline phosphatase is associated with lower levels of PPi and vascular calcification present in patients with chronic kidney disease.
- Shipping Conditions:
- Blue Ice