Mouse GAL3 Antibody Pair Set

Size

£793.80

Was £882.00

SKU:: E-KAB-0690
Additional Names:: LGALS3,CBP35,GALBP,GALIG,L31,LGALS2,MAC2,Lectin,Galactoside-Binding Soluble 3
Application:: ELISA
Physical State:: Other Biological Fluid, Plasma, Serum
Species Reactivity:: Mouse
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Reactivities:: Mouse
Buffer:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Immunogen:: GAL3
Formulation:: Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4, Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
Uniprot:: P16110
Synonyms:: 35 kDa lectin;carbohydrate-binding protein 35;CBP 35;ga;gal-3;gal3;galactose-specific lectin 3;galect;galectin-3;GBP;igE-binding protein;L-3;L-34;L-34 galactoside-binding lectin;laminin-binding protein;lectin L-29;Mac-;Mac-2;mac-2 antigen
Extra Details:: Galectin-3 is a member of the lectin family,which includes 15 mammalian lectin members. Like all galectins,galectin-3 contains a carbohydrate recognition binding domain of about 130 amino acids that enables the specific binding of B Beta-galactosides. This protein has been shown to be involved in cell adhesion,cell activation,chemoattraction,cell growth and differentiation,cell cycle,and apoptosis. Galectin-3 induces pro-inflammatory cytokines and inhibits Th2 type cytokine production. It chemoattracts monocytes and macrophages,and activates and degranulates basophils and mast cells. Galectin-3 has been shown to be involved in cancer,inflammation,fibrosis,heart disease,and stroke. It has also been shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure,including myofibroblast proliferation,tissue repair,inflammation,fibrogenesis,and ventricular remodeling. In addition,galectin-3 was found to contribute to tumor cell evasion of the immune system. Galectin-3 is increasingly being used as a diagnostic marker for different cancers. It can be screened for and used as a prognostic factor to predict the progression of the cancer.

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