E-KAB-0652
Rat IL-6R Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0652
- Additional Names:
- IL6R,CD126,IL-6R-1,IL-6R-Alpha,IL6Q,IL6RA,IL6RQ,gp80
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Rat
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Rat
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- IL-6R
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P22273
- Synonyms:
- IL-6R 1
- Extra Details:
- Part of the receptor for interleukin 6. Binds to IL6 with low affinity,but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response,acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling',the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively,'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
- Shipping Conditions:
- Blue Ice