E-KAB-0647
Human ACV-A Antibody Pair Set
Size
£460.80
Was £512.00
- SKU:
- E-KAB-0647
- Additional Names:
- ACV-A,Activin Beta A Beta A Homodimer
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Human
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Human
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- ACV-A
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- P08476
- Synonyms:
- activin beta-A chain;EDF;erythroid differentiation factor;erythroid differentiation protein;follicle-stimulating hormone-releasing protein;FRP;FSH-releasing protein;inhibin beta A chain;inhibin beta A subunit;inhibin, beta A (activin A, activin AB alpha polypeptide);Inhibin, beta-1
- Extra Details:
- The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition , serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion , it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore , the beta A subunit forms a homodimer , activin A , and also joins with a beta B subunit to form a heterodimer , activin AB , both of which stimulate FSH secretion. Finally , it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
- Shipping Conditions:
- Blue Ice