E-KAB-0620
Porcine IL-12 p40 Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0620
- Additional Names:
- CLMF2,IL-12 p40,IL-12/IL-23 p40,IL-12B,IL12 p40,IL12B,NKSF2,P40
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Porcine
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Porcine
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- IL-12 p40
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- Q28938, Q29053
- Synonyms:
- CLMF p35;CLMF p40;cytotoxic lymphocyte maturation factor 35 kDa subunit;cytotoxic lymphocyte maturation factor 40 kDa subunit;IL-12 subunit p35;IL-12 subunit p40;IL-12A;IL-12B;interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35);interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40);interleukin-12 p35 subunit;interleukin-12 p40 subunit;interleukin-12 subunit alpha;interleukin-12 subunit beta;interleukin-23 p40 subunit
- Extra Details:
- Associates with IL23A to form the IL-23 interleukin , a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R , activates the Jak-Stat signaling cascade , stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- Shipping Conditions:
- Blue Ice