E-KAB-0594
Mouse BAFF/CD257 Antibody Pair Set
Size
£793.80
Was £882.00
- SKU:
- E-KAB-0594
- Additional Names:
- TNFSF13B,BLYS,TALL1,THANK,TNFSF20,ZTNF4
- Application:
- ELISA
- Physical State:
- Other Biological Fluid, Plasma, Serum
- Species Reactivity:
- Mouse
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Reactivities:
- Mouse
- Buffer:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Immunogen:
- BAFF/CD257
- Formulation:
- PBS with 0.04% Proclin 300, 50% glycerol, pH 7.5, PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.5
- Uniprot:
- Q9WU72
- Synonyms:
- b cell-activating factor;B-cell-activating factor;BAF;BAFF;BL;BLyS;D8Ertd387;D8Ertd387e;TAL;TALL-1;TALL1;THANK;TNFSF20;Tnlg7a;tumor necrosis factor ligand 7a;tumor necrosis factor ligand superfamily member 13B;zTNF;zTNF4
- Extra Details:
- B cell-activating factor ( BAFF ) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus ( SLE ) . Also , some SLE patients have increased levels of BAFF in serum. Therefore , it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
- Shipping Conditions:
- Blue Ice